Wrong, GTX 1080 is 4 outputs. It has 5 physical outputs ( 1 DVI, 1 HDMI and 3 DP) but you can only use 4 simultaneously.Pls correct me if i am wrong!GTX 1080 only got 5 outputs.
Correct, SLI will use the slave card to increase the graphics capacity but disable the outputs on that card.Base on my experience if you running on 2 gpu SLI configuration you will still only had 5 outputs,if you got six projector to hook up it will not works for ur rig too.
There will be no know performance advantage to using SLI with Resolume so it'd be better to use the two GTX 1080 cards. That will give a total of 8 outputs (1 UI + 7 available with 3 on the main card and 4 on the secondary card).
Keep in mind that using a secondary card will result in a performance hit but the GTX 1080 is a powerful card so it should be fine.