You're really pushing what all you can accomplish with one piece of software, aren't you, eh?
Not saying it can't be done, I've controlled light's for a very small Stageline SL100 show with Resolume before, But the light's were static and I was just changing colors.
There's been a few method's of doing this before. There was an FX plugin for Arena 5 floating around somewhere that gives you a bunch of FX parameters that affect the DMX channel, and you can map those channels to you MIDI controller. I don't know if it has been converted to a 64-bit plugin for Arena 6 or not.
The method I used was:
Create a white cube in Photoshop or MS-Paint (I made mine the same size as my comp), then convert it to a single frame DXV3.
Create a new group and label it DMX, and add the following layers into that group.
Create a layer for however many DMX channels you wish to modify, and set that layer to trigger first clip on load.
Turn each of those layer's video opacity to 0.
Add on of those cubes to each one of those layers on column one.
Go into the advanced output and create a new screen and set the screen's output to virtual device.
Create a new DMX fixture for each of the layers you have created and assign one layer to one slice. (I labeled my layers: "SL Light 1 Red", "SL Light 1 Blue", so on, and so on)
Label your new DMX fixtures like you did your layers (I labeled my DMX fixtures: "SL Light 1 Red", "SL Light 1 Blue", so on, and so on).
Now Address those DMX fixture slices to match your lighting plot.
Create a new screen and set it to your output device, and add however many slices you need for it.
Close out of advanced output and create a new group and label it Video.
Add video layers to your choice and add your FX to those layer, clips, or group. Any FX that you want to add to your video group that you also want your light's to follow, you will need to copy that FX into the DMX group and map both of those FX to the same button.
From here, it's just a matter of mapping your DMX layer video opacity to buttons and knobs/faders.
You can create custom buttons that map those attributes to a certain value (DMX layer 1[red] to 50% and DMX layer 2 [green] to 50% to get a yellow color).
Keep in mind, the more DMX channels and layers you make is really going to dig into your system's performance.
So if you're wanting to run a 6 Universe light show from Resolume, you have more ball's than I do
There a right tool's for each job, It's all about knowing what your tool's limit's are.
The one thing I LOVE about Resolume is, they really don't limit themselves to be labeled "this or that", they don't put themselves in a box. They leave that door wide open for their end users to push themselves and the boundaries of their application. It's a beautiful thing!
Good luck!
Please post some pictures of your final result. Would love to see what you've made.
There might be an easier way to accomplish this, but this is the method I used. I had about 32 DMX layers and slices, I left them at the top of my comp and didn't see them while running my show. I controlled the stage wash with them and for the basic setup I did, It worked great. Saved the client about $200 in a lighting console rental.
Search the forum. I bet there's a few topic's that people created showing their DMX setup.
You will need an Artnet to DMX node of some kind to make the connection.