I''m trying to recreate the problem and thus far I've had no succes (or failure

I'm starting to think that this might be some USB-bandwith issue.. Although it's strange that this behavior is "new" to 4.1.1. Are you guys using any other USB-periphals when it happens? How about HD-activity, does it happen as well when playing no clips?
Mac users (I think a pc won't like it): what happens when you yank out the usb-lead and reconnect it, without quitting Avenue / Arena? (if the device doesn't respont, hit refresh in the midi preferences)
Any other system info is really appreciated!
Thanks,
Tim